Experiments and Sanity

Sometimes our experiments get very complicated and there are some tricks that can help prepare better. Today I want to share with you what helps me navigate high-stress experiment days like these.

1️⃣ Plan, Plan, Plan

Some days, I dedicate time just to planning: mapping out protocols, gathering supplies, and mentally walking through the entire experiment to anticipate challenges. This saves me from last-minute surprises.

2️⃣ Keep Master Protocols

Every time I learn a new experiment, I start with someone’s written protocol and then refine it. I add details like exact locations of materials, catalog numbers, and whether incubation for 1 hour vs. 2 hours really matters. The little details can make a big difference.

3️⃣ Check Inventory (Before It’s Too Late)

Ever started an experiment only to realize you’re out of a critical reagent? I’ve had my fair share of running from lab to lab, hunting for 5 µL of something I thought I had. Now, I check inventory before starting. Lesson learned.

4️⃣ Work in Teams

For big experiments—having a helper is a game changer. Team-tagging with co-authors or lab mates makes everything more efficient (and keeps you sane).

5️⃣ Stay Clean & Organized

Decluttering, decontaminating, and staying as clean as possible actually makes a difference. If nothing else, it makes you feel better. Trust me.

6️⃣ Reward Yourself

Difficult experiment ahead? I mentally prepare by setting up a reward system. My personal trick? Moving beads from one container to another as a little victory tracker. Sounds silly, but it works!

What’s one experiment or protocol you struggled with but eventually mastered? Any tricks that made it easier?